Best Evidence Review of Dietary Supplements and Mortality Rates in Older Women
Mursu J, Robien K, Harnack LJ, Park K, Jacobs Jr DR. Dietary supplements and mortality rate in older women. Arch Intern Med. 2011;171:1625-1633.
- Nearly half of older adults routinely use dietary supplements, with higher rates of use among women compared with men.
- The routine use of many dietary supplements is discouraged in practice guidelines.
- The use of multivitamins, vitamin B6, folic acid, iron, magnesium, zinc, and copper was associated with a higher risk for mortality among older women in the current study.
- Conversely, calcium supplements were associated with a lower risk for mortality.
- Physicians need to analyze nonprescription therapies used by patients and warn them of potential harms associated with the use of supplements.
Vitamins should not replace healthy, fresh, non-processed food!


